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Index > Protein center > Penk(Gene name) > Rat
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  • Penk (Gene name),
  • Proenkephalin-A (Protein name ),  PENK_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Penk(Penk-rs;Penk1);
    Protein name:
    Proenkephalin-A;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(239-260) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    269
    Sequence:
    50:
    MAQFLRLCIW | LLALGSCLLA | TVQADCSQDC | AKCSYRLVRP | GDINFLACTL | 
    100:
    ECEGQLPSFK | IWETCKDLLQ | VSKPEFPWDN | IDMYKDSSKQ | DESHLLAKKY | 
    150:
    GGFMKRYGGF | MKKMDELYPV | EPEEEANGGE | ILAKRYGGFM | KKDADEGDTL | 
    200:
    ANSSDLLKEL | LGTGDNRAKD | SHQQESTNND | EDSTSKRYGG | FMRGLKRSPQ | 
    250:
    LEDEAKELQK | RYGGFMRRVG | RPEWWMDYQK | RYGGFLKRFA | ESLPSDEEGE | 
    269:
    SYSKEVPEME | KRYGGFMRF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Proenkephalin-A
    Cat.:
    E0279h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Proenkephalin-A
    Cat.:
    E0279r
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    Packing:
    96T
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    ELISA Kit for Rat Proenkephalin-A
    Cat.:
    E0279m
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    96T
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    ELISA Kit for Rat Proenkephalin-A
    Cat.:
    E0279b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Proenkephalin-A
    Cat.:
    U0279h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Proenkephalin-A
    Cat.:
    U0279m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Proenkephalin-A
    Cat.:
    U0279b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Proenkephalin-A
    Cat.:
    U0279r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Proenkephalin-A
    Cat.:
    P0279Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Proenkephalin-A
    Polyclonal Antibody for Rat Proenkephalin-A
    Cat.:
    P0279Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Proenkephalin-A
    Cat.:
    P0279Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Proenkephalin-A
    Monoclonal Antibody for Rat Proenkephalin-A
    Monoclonal Antibody for Rat Proenkephalin-A
    Monoclonal Antibody for Rat Proenkephalin-A
    Protein for Rat Proenkephalin-A
    Protein for Rat Proenkephalin-A
    Protein for Rat Proenkephalin-A
    Protein for Rat Proenkephalin-A

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    Precision
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    Linearity
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    References
    1. 1.
      "Rat brain preproenkephalin mRNA. cDNA cloning, primary structure, and distribution in the central nervous system."
      Yoshikawa K. , Williams C. , Sabol S.L.
      J. Biol. Chem.259:14301-14308(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Fischer 344.
      tissue: Brain.
    2. 2.
      "Isolation and characterization of the rat proenkephalin gene."
      Rosen H. , Douglass J. , Herbert E.
      J. Biol. Chem.259:14309-14313(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: Fischer 344.
    3. 3.
      "Molecular cloning and sequence determination of rat preproenkephalin cDNA: sensitive probe for studying transcriptional changes in rat tissues."
      Howells R.D. , Kilpatrick D.L. , Bhatt R. , Monahan J.J. , Poonian M. , Udenfriend S.
      Proc. Natl. Acad. Sci. U.S.A.81:7651-7655(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Fischer 344.
      tissue: Brain.
    4. 4.
      "Proenkephalin biosynthesis in the rat."
      Howells R.D.
      NIDA Res. Monogr.70:43-65(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    5. 5.
      "A new species of enkephalin precursor mRNA with a distinct 5'-untranslated region in haploid germ cells."
      Yoshikawa K. , Maruyama K. , Aizawa T. , Yamamoto A.
      FEBS Lett.246:193-196(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Wistar.
      tissue: Testis.
    6. 6.
      "Molecular cloning, sequence analysis and translation of proenkephalin mRNA from rat heart."
      Rao S.M. , Howells R.D.
      Regul. Pept.40:397-408(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Heart.
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Testis.
    8. 8.
      "Discovering new bioactive neuropeptides in the striatum secretome using in vivo microdialysis and versatile proteomics."
      Bernay B. , Gaillard M.-C. , Guryca V. , Emadali A. , Kuhn L. , Bertrand A. , Detraz I. , Carcenac C. , Savasta M. , Brouillet E. , Garin J. , Elalouf J.-M.
      Mol. Cell. Proteomics8:946-958(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 114-133; 143-185 AND 239-260;FUNCTION;MASS SPECTROMETRY
      strain: Wistar.
      tissue: Corpus striatum.
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